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The author has long been interested in how plant derived substances
can prove beneficial to Medicine. Writings on papyrus from the earliest
times have described the use of willow bark for soothing inflamed wounds.
Major contributions by the Reverend Edward Stone of Chipping Norton,
and Dr. Thomas Maclagan of Dundee are covered, along with the unique
discovery by Professor John Vane and his team, of the fundamental effect
of aspirin on prostaglandin synthesis. The book includes fascinating
memorabilia on the early days of aspirin, kindly donated from the Bayer
archive.
In his first book on the foxglove, the author described how Natures
gift of digitalis came to become accepted worldwide as a valuable treatment
for heart failure. Now, he has explored the bark of the willow, from
which by chemical modification, aspirin was obtained. But whereas up
to now, digitalis (in its current form, digoxin), only has a place in
the treatment of heart disease, aspirin the worlds most
ubiquitous pain killer, has in the last half-century, been shown also
to prevent heart attacks and strokes. And in addition it may soon come
into use in cancer prevention.
The author is currently a practising consultant rheumatologist at Leicester
Royal Infirmary who, in former years, prescribed prodigious amounts
of aspirin for the treatment of rheumatoid arthritis. As an immunologist
at the University of Leicester, he has taught medical students from
the inception of its medical school.
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